PARITUTU SERUM DIOXIN STUDY TIMELINE 2004-2011 DRAFT .
In 2004 when elevated serum TCDD was detected the MoH set up a unit to manage potential*01 financial risks.
The peer reviewed study design and ethical consent specified the study would target 1962 to 1975 residents.
The MoH re-targeted Part II at 1974-87 those least likely to be highly exposed while claiming the direct opposite.
ESR warned*03 the proposed MoH course of action was potentially misleading opposing MoH re-targeted testing.
This extended the period of exposure away from the 1960-72 periods through the low exposure 1973-87 periods.
Oct. 2006 In TV3 Doco ‘Let Us Spray’ Forensic Accountant John Leonard supports community claims of errors in serum report.
MoH misled the Minister who misled Parliament*27 claiming initial peer reviews had received anonymised results.
Reviews did not recognise ESR reports outdated 0-18 years half life values*35 had skewed pre 1974 results.
Bias to lower 2004 levels in younger pre 1974 subjects resulted in flawed conclusions over timing of exposures.
The 2007 media conference did not tele-link the only peer reviewer*36 with participants key individual data.
MoH, ESR & Dr Fowles [ex ESR] continue to ignore key suggestions of the only*36 ever review with key data. e.g.
: correct and clarify, so that the text and tables match.
: revisit pre vs post 1974 exposure levels: Part II set out to investigate (the still unreported) 1974-87 exposures:
: instead the low exposure 1974-87 results are still blended with significantly increased 1962-87 results.
: outliers. e.g. 11.8 and 17.9 ppt were the only 2 highly significant Part II results, both had pre 1974 exposures.
: illustrate 1/2 lives e.g. Appendix P ages 0-18 years . Five pre 1974 subjects were unlikely to exhibit a 2004 increase.
MoH used the BSA process without discovery and disclosure to create a perception the study was not*46 skewed.
The new 2009 report stated increased TCDD was found primarily [not *exclusively] pre 1968 study participants .
The new report continued to blend low results from samples assessing 1974-87 periods with high 1962-87 results
Although the new report eliminated some errors, it did not recheck the key residence period for the *17.9pg/g result.
The 17.9 pg/g TCDD result of subject 1408 was the only *highly significant evidence of 1974 to 1987 exposures.
In 2010 asked for evidence of Part II 1974-87 exposure other than 17.9 pg/g (1408), Fowles cited three Part I results.
Fowles purports low 2004 levels in two 1968-74 subjects*43 vs the highest 2004 level in an adult 1968-86 subject.
MoH ‘spun’ data to claim 1962 to 87 exposure, masking that highly significant results were exclusive to 1960-72.
MoH used young 1962-74 subjects low levels to claim 1962-87 residence was key to increases, instead of 1960-72.